What do we currently know about the clinically isolated syndrome suggestive of multiple sclerosis? An update

T Grzegorski, J Losy - Reviews in the Neurosciences, 2020 - degruyter.com
… also include isolated brainstem syndromes, cerebellar involvement, … Prediction based on
machine learning techniques is very … of conversion to MS is to estimate the risk of the disease

[HTML][HTML] Cerebellar and/or brainstem lesions indicate poor prognosis in multiple sclerosis: a systematic review

Y Yang, M Wang, L Xu, M Zhong, Y Wang… - Frontiers in …, 2022 - frontiersin.org
… and the progression of clinically isolated syndromes (CIS) to … CIS has a higher risk of early
conversion to MS (HR, 2.0; 95% … have no statistical significance for predicting prognosis (18, …

[HTML][HTML] Evaluating magnetic resonance diffusion properties together with brain volumetry may predict progression to multiple sclerosis

J Stulík, M Keřkovský, M Kuhn, M Svobodová… - Academic …, 2022 - Elsevier
DTI parameters together with brain volumetry in patients with early-stage CIS may be useful
in predicting conversionClinically isolated syndrome (CIS) is a monophasic clinical episode …

[HTML][HTML] MRI prognostic factors in multiple sclerosis, neuromyelitis optica spectrum disorder, and myelin oligodendrocyte antibody disease

R Cortese, A Giorgio, G Severa… - Frontiers in Neurology, 2021 - frontiersin.org
… In patients with the clinically isolated syndrome (CIS), a higher number … non-lesional tissue
and along specific WM tracts (71, 72). These techniques include diffusion tensor imaging (DTI

[HTML][HTML] Default mode network structural integrity and cerebellar connectivity predict information processing speed deficit in multiple sclerosis

G Savini, M Pardini, G Castellazzi… - Frontiers in cellular …, 2019 - frontiersin.org
… exclusion: from the JHU ICBM-DTI-81 atlas, provided with FSL in … not to separate tissue in
lesional and non lesional masks. … the clinical translation potential of network measures for the …

MRI biomarkers of disease progression and conversion to secondary-progressive multiple sclerosis

E Tavazzi, R Zivadinov, MG Dwyer… - Expert Review of …, 2020 - Taylor & Francis
… , both within focal lesions and in the non-lesional tissue of both … with a so-called
clinically isolated syndrome, and is a … in this regard than traditional DTI-based measures [Citation113]. …

[HTML][HTML] MRI biomarkers of disease progression in multiple sclerosis: old dog, new tricks?

Y Barnett, JY Garber, MH Barnett - Quantitative Imaging in …, 2020 - ncbi.nlm.nih.gov
… MS/CIS patients with conversion to disability progression compared to … in a cohort of patients
with clinically isolated syndrome (CIS) and MS. … metrics, such change in lesion DTI or MTR. …

[HTML][HTML] Classification of multiple sclerosis clinical profiles via graph convolutional neural networks

A Marzullo, G Kocevar, C Stamile… - Frontiers in …, 2019 - frontiersin.org
… Ninety MS patients (12 clinically isolated syndrome, 30 relapsing-… of a shorter conversion
into a clinically definite MS (Kugler and … of MS clinical profiles based on brain DTI acquisition. …

[HTML][HTML] Patterns of brain atrophy in recently-diagnosed relapsing-remitting multiple sclerosis

R Meijboom, EN York, A Kampaite, MA Harris… - PLoS …, 2023 - journals.plos.org
… image with a rigid body transformation (degrees of freedom = … with clinical changes in clinical
isolated syndrome (CIS) or … (DTI) to explore cerebellar changes in RRMS have observed …

[HTML][HTML] Uncovering convolutional neural network decisions for diagnosing multiple sclerosis on conventional MRI using layer-wise relevance propagation

F Eitel, E Soehler, J Bellmann-Strobl, AU Brandt… - NeuroImage: Clinical, 2019 - Elsevier
… information such as lesion location, non-lesional white matter or … the JHU ICBM-DTI atlas,
separately for MS patients and healthy … questions such as predicting disease progression or …